22 Second Street E
Frederick, Maryland 21701

New / MLS #MDFR2073594 / Commercial / Mixed Use / Frederick
Listing information updated 11/17/2025 at 9:21pm
Experience the charm and convenience of historic Downtown Frederick at 22 E 2nd Street. This beautifully maintained office building offers up to seven individual offices across three levels, providing flexible configurations for solo practitioners, small teams, or growing businesses. A full kitchen and washer/dryer hookups add comfort and practicality for day-to-day operations. With its classic architecture and walkable location, this property is ideal for professional office users, mental health providers, consulting firms, and health or wellness services seeking an inviting, comfortable, and centrally located workspace.

Listing Office: MacRo, Ltd.

Listing Office Phone: 301.698.9696

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Map of 22 Second Street E, Frederick, MD 21701

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22 Second Street E, Frederick, MD 21701 is a commercial / mixed use currently listed at $20 | $20/sq. ft.. This commercial / mixed use has been listed on RLAH @properties since November 17th, 2025 and was built in 1880.