4053 Market Street

4053 Market Street
PHILADELPHIA, Pennsylvania 19104

Price Change / MLS #PAPH2631170 / Commercial / Mixed Use / PHILADELPHIA
Listing information updated 6/15/2026 at 10:01pm
Prime University City Commercial Opportunity at 40th & Market! Offering +/- 2,200 SF of premium ground-floor space with high-visibility Market Street frontage. Situated in a high-density, mixed-use building directly adjacent to the University of Pennsylvania and Drexel University campuses. PROPERTY HIGHLIGHTS: (1) Zoning: CMX-4 (High-Density Commercial Mixed-Use) allows for a wide array of uses by-right. (2) Foot Traffic: Exceptional pedestrian volume driven by tens of thousands of nearby students, healthcare professionals, and residents. (3) Transit-Oriented: Immediate, steps-away access to the SEPTA Market-Frankford Line (40th St Station), trolley lines, and bus routes. (4) Layout: Flexible, open layout adaptable for diverse builds. Features prominent storefront exposure along Market Street. IDEAL USES: Perfect for Medical/Dental Clinics, Physical Therapy, Professional Office, Daycare, Educational Services, Specialty Retail, Cafes, Tech Showrooms, Wellness Centers, Daycare, or Restaurant. LOCATION ADJACENCIES: Unbeatable location in Philadelphia's most dynamic innovation district, minutes from Penn Medicine, Children's Hospital of Philadelphia (CHOP), and major science/tech hubs. Leverage the massive daytime population and unparalleled visibility in one of the city's most rapidly growing commercial corridors. Schedule your tour today!

Listing Office: Keller Williams Main Line

Listing Office Phone: 610.520.0100

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4053 Market Street, Philadelphia, PA 19104 is a commercial / mixed use currently listed at $6,800 | $6,800. This commercial / mixed use has been listed on RLAH @properties since June 6th, 2026 and was built in 1965.